Some weapons can be crafted at a Work Bench or a Pre-Hardmode/Hardmode Anvil, while others can only be found in Chests, as enemy drops, or purchased from NPCs. This page contains a sortable list of all available weapons in Terraria.
The best gun is the Zapinator, which was removed from the game. Weapons are essential items used for combat against enemies, bosses, and even other players during PvP games.Most weapons are crafted at any crafting Station, while others can only be found in Chests, as enemy/boss drops, or purchased from NPCs.The Calamity Mod adds a large number of new and unique weapons for players to use. The best USABLE gun, again, depends on your playstyle. Terraria has a wide variety of weapons and weapon classes, each suited to particular play styles or specific tasks. But really, the best sword is the Terra Blade or the Horseman's blade, best spear is the Mushroom Spear, the best flail is the Flairon, and the best spell is just a matter of one's playstyle.

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Weapons are essential items used for combat against enemies, bosses, critters, and even other players during PvP games.